Think Rare, Act Early:
Metachromatic Leukodystrophy

Progressive Neurodegeneration in Children: Are We Diagnosing Too Late?

This webinar addresses the challenge of recognizing progressive neurodegeneration in children, a significant but under-recognized clinical burden that is frequently diagnosed late. Led by Prof. Nicole Wolf, Dr. Serena Gasperini, and Prof. Samuel Gröschel, the session focuses on identifying early clinical red flags, distinguishing progressive neurodegeneration from other pediatric presentations, and applying a structured approach to investigation and referral. Using case models from MLD and MPS III, participants will gain practical insight into how these conditions present in clinical practice and how earlier recognition can support timely decision-making and improve patient and family outcomes.