Introduction: H pylori is a bacterium that can infect infants mainly by person-to-person transmission via oral or fetal through the family or dirty hands. Its diagnosis requires invasive methods such as endoscopy and biopsy. Although there are non-invasive methods, it is important to take into account the growing resistance to antibiotics in the pediatric population, which may require adjusting the treatment.In the last 10 years, the pediatric group has had a guide prepared by experts from the pediatric gastroenterology societies of Europe (ESPGHAN) and the United States (NASPGHAN) published in 2011 and updated in 2017 that has guided us in the management of infection by H. Pylori in pediatric age.Summary: The case is presented of an infant who was diagnosed and treated for presenting spontaneous vomiting in no. of 4-6- 10, on different occasions with intervals of two weeks, spontaneously, without an apparent cause or other symptoms. , entering the emergency service, negative analysis, and normal ultrasounds, as well as general coprology. In the last admission, active chronic gastritis and food sensitizations were diagnosed, with the determination of positive antigen in feces. I also present continuous hiccups and belching plus diarrhea, without fever, repercussions of the state of hydration, or the intake of liquids and solids, it was managed with doses of intramuscular ondansetron on both occasions and probiotics, clinically, without malnutrition data.The infection can cause digestive problems and treatment is based on a triple antibiotic therapy and a proton pump inhibitor for 14 days. The management of infection in children is a permanent dilemma in clinical practice. Over the years, a multitude of questions have been created regarding the symptoms linked to the infection, the diagnostic methods and the methods of treatment, the most controversial being the diagnostic indication.

